Abstract
There have been various reports of side effects of betadimethylaminoethyl benzhydryl ether hydrochloride (Benadryl). 1 These reports describe, among others, symptoms of nervousness and/or of hyperirritability. McElin and Horton la reported several cases of difficulty in coordination; Waldbott, 1b muscular twitchings, and Levin, 1c narcolepsy, confusion, jitters and irritability. This is the report of a case in which the symptoms of nervousness, difficulty in coordination and muscular twitchings were present to the extent of epileptiform movements. REPORT OF A CASE J. H. W., a white boy aged 3 1/2, weight 33 pounds (15 Kg.), had symptoms of hay fever for the first time in August and September 1945. Scratch tests confirmed sensitivity to ragweed (giant and short varieties) only, and in December 1945 treatment was instituted for hyposensitization. Treatment was given until June 9, 1946, and then the child left town. At that time he was receiving 6,000 pollen units
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