Abstract
Two novel sulfated sterols, ibisterol sulfates B ( 3) and C ( 4), and an unprecedented non-sulfated sterol, 4β,5β-epoxy-2β,3α,12β,22 S-tetrahydroxy-14α-methylcholest-7,9(11)-dien-6,24-dione ( 5) have been isolated from a Xestospongia sp. collected in the Philippines. The structures were elucidated using spectroscopic data. These sterols were found to be inhibitors of HIV-1 integrase.
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