Unusual Peripheral Neuropathies. Part II: Intrinsic Reactive Causes

Abstract

Peripheral neuropathy is common with many different etiologies. This is the second of three articles to review the less-common causes of peripheral neuropathy. Part II reviews the intrinsic "reactive" causes of peripheral neuropathy, including those related to connective tissue, vasculitis, sarcoid, organ failure, and inflammatory bowel disease. The extrinsic causes of neuropathy and the induced or inherited causes of neuropathy are covered in separate articles in this issue of SEMINARS IN NEUROLOGY, Part I and Part III, respectively. The brief series of reviews of causes of neuropathy describe common presentations and constellation of clinical findings. The goal is to help the practicing clinician increase the diagnostic yield when sorting out the unusual causes of peripheral neuropathy.