Unusual lesion in the splenium of the corpus callosum and coronavirus infectious disease-19

Nivedita Agarwal,Rosella Martini,Giovanni Pedrotti,Sabino Walter Della Sala

doi:10.1259/bjrcr.20200068

Nivedita Agarwal, Rosella Martini + Show 2 more

Open Access

https://doi.org/10.1259/bjrcr.20200068

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Journal: BJR\|case reports	Publication Date: Jul 3, 2020
Citations: 6	License type: cc-by

Affiliation: University of Trento, Ospedale Santa Maria

Abstract

Coronavirus infectious diseases (COVID-19) is an emerging infectious disease that has taken a strong grip on the entire global community. The diagnosis per se is straightforward; however, the disease seems to affect multiple organs. Cytokine-storm, increased thromboembolic state, deranged overall homeostasis and aggressive medical treatment can cause a variety of lesions in the central nervous system. Interpretation of brain imaging findings will require a thorough understanding of the clinical status of the patient and treatment being offered, keeping in mind the several ways in which the viral pathogen, severe acute respiratory syndrome coronavirus-2 may interact with brain tissue. We present differential diagnosis of a MRI identified solitary lesion in the splenium of the corpus callosum, in a COVID-19 positive patient with altered mental status.

Highlights

On March 11, 2020, the World health organization declared a pandemic outbreak caused by a novel coronavirus, severe acute respiratory syndrome coronavirus
We present differential diagnosis of a magnetic resonance imaging identified solitary lesion in the splenium of the corpus callosum, in a COVID-19 positive patient with altered mental status
Such aggressive treatment may result in several brain parenchymal lesions which may or may not be directly related to SARS-CoV-2.We describe here the CT and magnetic resonance imaging (MRI) findings from a patient with COVID-19 where a lesion in the splenium with subsequent hemorrhage has been identified

Summary

Introduction

On March 11, 2020, the World health organization declared a pandemic outbreak caused by a novel coronavirus, severe acute respiratory syndrome coronavirus Interpretation of brain imaging findings will require a thorough understanding of the clinical status of the patient and treatment being offered, keeping in mind the several ways in which the viral pathogen, severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) may interact with brain tissue.

Results

Conclusion