Abstract
An 11-year-old American boy was staying with his family in Indonesia. He presented with a 5-month history of recurrent bruises and ecchymosis. A clinical diagnosis of acquired platelet dysfunction with eosinophilia was made when his full blood counts showed hypereosinophilia (7.4×109/L) with normal platelet count and gray platelets under the microscope. The diagnosis was supported by abnormal platelet aggregation tests consistent with a storage pool disorder. The bleeding symptoms and eosinophilia resolved a month later with a full course of antihelminthic therapy. Hematologists should be aware of this unusual disease in travelers returning from the Southeast Asia.
Highlights
With a 5-month history of recurrent bruises and ecchymosis
The diagnosis was supported by e abnormal platelet aggregation tests consistent s with a storage pool disorder
Hematologists should be aware of this ia unusual disease in travelers returning from c the Southeast Asia. mer Introduction m Acquired platelet dysfunction with o eosinophilia (APDE) is usually a self-limiting c bleeding disorder characterized by an insidious onset of easy bruising with petechiae in an n otherwise well person.[1]
Summary
A clinical diagnosis of ly acquired platelet dysfunction with eosinophilia was made when his full blood counts showed n hypereosinophilia (7.4×109/L) with normal o platelet count and gray platelets under the microscope. The diagnosis was supported by e abnormal platelet aggregation tests consistent s with a storage pool disorder.
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