Abstract
Fungal infections are an important cause of morbidity and mortality in renal transplant recipients. The causative agent and the risk factors differ depending on the period after the kidney transplant. Also the incidence varies according to the geographical area. We are reporting three cases of fungal infections in renal transplant recipients. Two of them have etiological agents which are common among immunosuppressed patients, but with an atypical clinical presentation, while one of them is a subcutaneous infection caused by a less frequent dematiaceous fungus, Aureobasidium pullulans. These cases highlight how a high index of clinical suspicion and prompt diagnosis is very much essential for better outcome. The emerging fungal infections and paucity of data regarding their management pose a challenge to the transplant physicians.
Highlights
Fungal infections account for 5% of all infections in renal transplant recipients [1]
In an Indian study 6.1% of renal transplant recipients were affected by systemic fungal infections and resulted in a 63% mortality rate [3]
Two of them have etiological agents which are common among immunosuppressed patients, but with an atypical clinical presentation, while one of them is a subcutaneous infection caused by a less frequent dematiaceous fungus, Aureobasidium pullulans
Summary
Fungal infections account for 5% of all infections in renal transplant recipients [1]. Because of environmental exposure and the effects of immunosuppressive regimens, systemic mycosis is a significant problem in transplant patients worldwide and remains the major cause of death in those individuals [2]. In an Indian study 6.1% of renal transplant recipients were affected by systemic fungal infections and resulted in a 63% mortality rate [3]. The causative agent and the risk factors differ depending on the period after the kidney transplant. We report three cases of fungal infection in renal transplant recipients. Two of them have etiological agents which are common among immunosuppressed patients, but with an atypical clinical presentation, while one of them is a subcutaneous infection caused by a less frequent dematiaceous fungus, Aureobasidium pullulans
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