Unusual Etiology of Acute Myocardial Infarction – Factor V Leiden Mutation

Abstract

The genetic defect of coagulation factor V known as factor V Leiden produces a resistance to degradation of factor V by activated protein C (APC) and that will increase the risk of venous thromboembolism. The data on arterial thrombosis and acute myocardial infarction associated with APC resistance are still not clearly defined. We report a case of acute myocardial infarction in young patient with no cardiovascular risk factors and the etiology of the myocardial infarction was defined as acute arterial thrombosis associated with factor V Leiden defect, without any significant coronary lesions. Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"جدول عادي"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;}