Abstract
In October 2015, a new case of Ebola virus disease in Guinea was detected. Case investigation, serology, and whole-genome sequencing indicated possible transmission of the virus from an Ebola virus disease survivor to another person and then to the case-patient reported here. This transmission chain over 11 months suggests slow Ebola virus evolution.
Highlights
In October 2015, a new case of Ebola virus disease in Guinea was detected
Subissi) epidemiologic and molecular evidence of an unusual chain of Ebola virus (EBOV) transmission. This chain includes an Ebola virus disease (EVD) survivor, who recovered in December 2014; possibly his wife or a third unknown person; and the woman’s brother, who became ill with EVD in October 2015
The Study On October 8, 2015, the case-patient in Conakry, Guinea, became ill with fever and appetite loss. His brother-in-law, an EVD survivor and nurse living in the same household, diagnosed malaria, but the case-patient did not respond to malaria treatment; diarrhea, headache, and abdominal pain developed
Summary
In October 2015, a new case of Ebola virus disease in Guinea was detected. Case investigation, serology, and wholegenome sequencing indicated possible transmission of the virus from an Ebola virus disease survivor to another person and to the case-patient reported here. Author affiliations: World Health Organization, Conakry, Guinea This chain includes an EVD survivor, who recovered in December 2014; possibly his wife (the woman) or a third unknown person; and the woman’s brother, who became ill with EVD in October 2015 (the case-patient).
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