Abstract
The case reported herein consists of nodular pulmonary amyloidosis presenting with unusual cystic radiological features which reveal a pulmonary localisation of an extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). The present case is the first to report a radiological presentation of nodular pulmonary amyloidosis in the absence of Sjögren's syndrome. Although transthoracic fine-needle biopsy was helpful for the diagnostic of amyloidosis, final diagnosis of associated MALT-type lymphoma required an open lung biopsy. This emphasises the importance of performing surgical investigations in pulmonary nodular amyloidosis in order to depict the presence of underlying lung tumours or lymphoproliferative disorders.
Highlights
Transthoracic fine-needle biopsy was helpful for the diagnostic of amyloidosis, final diagnosis of associated MALT-type lymphoma required an open lung biopsy
Whereas pulmonary A fine-needle transthoracic biopsy was peramyloid deposit demonstrated using fine- formed and showed amorphous eosinophilic needle biopsy [7], the present study reports a material suggestive of amyloidosis engulfed by case of nodular pulmonary amyloidosis present- giant cells and surrounded by a few crushed ing with unusual cystic features on the computed tomography (CT) scan, which, in relalymphocytes
The present authors report a case of a pulmonary localisation of MALT-type lymphoma associated with pulmonary nodular amyloidosis presenting with unusual findings on the CT scan
Summary
Transthoracic fine-needle biopsy was helpful for the diagnostic of amyloidosis, final diagnosis of associated MALT-type lymphoma required an open lung biopsy. Pulmonary nodular amyloidosis mainly occurs in formed as a result showed bone marrow involveelderly patients who harbour an indolent clinical ment by the same lymphoid proliferation and presentation; incidentally, nodules are most fre- confirmed its l monoclonality.
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