Abstract

Odontogenic neoplasms present with characteristic clinicoradiological presentation giving clue to their diagnosis. However, unusual presentations may confuse the clinician and diagnosis may become elusive. We encountered one such atypical presentation when a 60-year-old female presented with an unusually large cystic lesion in the mandibular midline, creating a diagnostic dilemma. Unicystic ameloblastoma (UA) presents with clinical and radiographic features of a jaw cyst but show a typical ameloblastomatous transformation of lining epithelium, with or without luminal and/or mural tumor proliferation on histologic examination. This variant differs from solid ameloblastoma in being less aggressive and being seen commonly in young individuals. Another unique fact about UA is that recurrence may be long delayed, and a long-term postoperative follow-up is essential for proper management of these patients.

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