Unusual clear cell tumors of the jaws – clinical and histopathological considerations: A case report

Giulio Gasparini,Francesco Federico,Alessandro Moro,Sandro Pelo,Federica Castri,Roberto Boniello

doi:10.1186/1752-1947-2-290

Giulio Gasparini, Francesco Federico + Show 4 more

Open Access

https://doi.org/10.1186/1752-1947-2-290

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Abstract

IntroductionClear cell neoplasms of the jaw are very infrequent and a review of the literature reports only isolated cases of metastatic renal clear cell carcinoma of the jaw.Case presentationA 68-year-old man presented with an osteolytic lesion of the left hemimandible. The first diagnostic hypothesis was a third molar follicular cyst. Surgical treatment consisted of enucleating the lesion preserving the alveolar nerve and extracting of the retained tooth. Unexpectedly, the lesion presented as a solid.ConclusionThe authors report a case of a clear cell neoplasm involving the jaw in which histopathological exam presented an indeterminate histology. The histological characteristics of this tumor make it unique in the international literature.

Highlights

Clear cell neoplasms of the jaw are very infrequent and a review of the literature reports only isolated cases of metastatic renal clear cell carcinoma of the jaw.Case presentation: A 68-year-old man presented with an osteolytic lesion of the left hemimandible
We report a case of a clear cell neoplasm involving the jaw in which histopathological exam presented an indeterminate histology
Lesion had spread into the linguo-vestibular thickness of the left hemimandible from the second premolar to the impacted third molar

Summary

Introduction

Clear cell neoplasms of the jaw are very infrequent and a review of the literature reports only isolated cases of metastatic renal clear cell carcinoma of the jaw.Case presentation: A 68-year-old man presented with an osteolytic lesion of the left hemimandible. Clear cell neoplasms of the jaw are very rare and a review of the literature reports only isolated cases of metastatic renal clear cell carcinoma of the jaw [1,2,3]. We report a case of a clear cell neoplasm involving the jaw in which histopathological exam presented an indeterminate histology. Upon panoramic (Fig. 1) and computed tomography (CT) DentaScan investigation, the osteolytic lesion was seen to involve the first and second molar apex with amputation of the mesial root apex of the first molar.

Results

Conclusion