Abstract

In 150 young (14-day-old) rats the duration of the DNA synthesis of myocytes and interstitial cells of the heart was investigated by double-labelling with 3H-thymidine, and by the technique of %-labelled mitoses. Both these methods showed the S-phase to last about 10 h for each of the above 2 cell types. The inhibition of muscle cell proliferation which takes place in the early stages of the postnatal heart growth does not seem to be caused primarily by a disturbance of their S-phase.

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