Abstract
We recently identified variances in serum metabolomic profiles between fasted diabetic and healthy dogs, some having similarities to those identified in human type 1 diabetes. Compare untargeted metabolomic profiles in the non-fasted state. Serum from non-fasted diabetic (n = 6) and healthy control (n = 6) dogs were analyzed by liquid chromatography-high resolution mass spectrometry. Clear clustering of metabolites between groups were observed, with multiple perturbations identified that were similar to those previously observed in fasted diabetic dogs. These findings further support the development of targeted assays capable of detecting metabolites that may be useful as biomarkers of canine diabetes.
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