Abstract

Preface 1. An Insuperable Problem 2. Nature's Solutions: The DNA Topoisomerases 3. Breaking a DNA Strand and Holding on to the Broken Ends 4. A Magic Swivel 5. Moving One DNA Double Helix through Another 6. Real-Time Viewing of the DNA Topoisomerases in Action 7. Manifestations of DNA Entanglement: Replication and Recombination 8. Manifestations of DNA Entanglement: Gene Expression 9. Beyond DNA Entanglement: New Twists on an Old Theme 10. From Nature's Battlefields to the Clinical Wards Appendices 1. Identification of the Covalent Intermediates in Topoisomerase-Catalyzed Reactions 2. Catalysis of DNA Breakage and Rejoining by DNA Topoisomerases Index

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.