Abstract
Abstract: India is well known for its broad spectrum diversity concerning cultural, lingual, and ethnic, aligned with caste, tribes, and community segments. Serving for the passage of human migration in history has been reported as the reason for this wide genetic variability in the Indian populations. With the aim to unravel the genetic structure of Kahar and Tharu people of India, 23 Y chromosomal paternal lineage markers were analyzed in 147 unrelated male Individuals (Kahar = 78 and Tharu = 69). The cumulative probability of matching for the Kahar and Tharu people was observed to be 2.94 × 10‐12 and 5.06 × 1012, respectively. Both the studied populations belong to the same geographical region but showed minute genetic distance between each other in population cross-comparison study. Haplogroup R was observed most frequently in the studied populations which are also reported to be the most prevalent in North Indian populations. The genetic distance between the studied and previously published populations was analyzed using the Analysis of Molecular Variance (AMOVA) and Multi-Dimensional Scaling (MDS) tool from the Y Chromosome Haplotype Reference Database (YHRD). The Studied populations come up with the genetically close Indian populations from Uttarakhand, Karnataka, Andhra Pradesh and Singapore, and Bangladeshi populations from Dhaka, which might be a result of genetic relatedness.
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