Abstract
Volatile oil from the root bark of Oplopanax horridus is regarded to be responsible for the clinical uses of the title plant as a respiratory stimulant and expectorant. Therefore, a supercritical fluid extraction method was first employed to extract the volatile oil from the roots bark of O. horridus, which was subsequently analyzed by GC/MS. Forty-eight volatile compounds were identified by GC/MS analysis, including (S,E)-nerolidol (52.5%), τ-cadinol (21.6%) and S-falcarinol (3.6%). Accordingly, the volatile oil (100 g) was subjected to chromatographic separation and purification. As a result, the three compounds, (E)-nerolidol (2 g), τ-cadinol (62 mg) and S-falcarinol (21 mg), were isolated and purified from the volatile oil, the structures of which were unambiguously elucidated by detailed spectroscopic analysis including 1D- and 2D-NMR techniques.
Highlights
Forty-eight volatile compounds were identified by GC/MS analysis, including (S,E)-nerolidol (52.5%), τ-cadinol (21.6%)
SFE was performed using the root bark of O. horridus (10 g, dried powder, 80 mesh) as sample which contained all of the volatiles
The results indicated that this GC/MS coupled with SFE method was precise and accurate for qualitative analysis of volatile components
Summary
Gray ex Miq., commonly known as Devil’s club, is a botanical exclusively originated from and grown in North America [1,2,3]. O. horridus has a long and well-known history of medicinal used for rheumatoid arthritis, autoimmune conditions, eczema, type II diabetes, external infections and internal infections, and Devil’s club extracts are marketed in North. America, where it eaten as a respiratory stimulant and expectorant [4,5,6]. The fresh juice from the root bark of Devil’s club is mostly used for respiratory diseases [5,6]. The volatile oil from the root bark of this plant is regarded as responsible for some clinical uses of the title plant [5,7]
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