Unsolved mysteries and controversies of mitochondria in the heart – A virtual special issue in JMCC: Part IV

Abstract

Five years ago, JMCC published a special issue that reviewed a number of exciting advancements in basic and translational research of mitochondrial biology [1]. It seemed that, with these breakthrough discoveries, many mysteries surrounding mitochondrial function and regulation were solved or could be solved by now. Undoubtedly, tremendous progress has been made during the past few years from widespread cutting-edge investigations on this research area; nevertheless, mysteries and controversies remain in several critical questions.