Abstract
The formation of O-substituted derivatives of 1-hydroxy-2(1H)-pyridone and 1-hydroxycarbostyril (cyclic hydroxamic acid esters) on treatment of 2-ethoxypyridine-1-oxide and 2-ethoxy-quinoline-1-oxide monohydrate, respectively, with primary and secondary halides is described. The interaction of 4-ethoxypyridine-1-oxide and benzyl halides under similar conditions afforded only the corresponding benzaldehydes. The mechanisms of these reactions are discussed.
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