Abstract
Hereditary gingival bromatosis is a rare condition that affects the gingiva and is characterized by a benign, brous overgrowth that can occur alone or as part of a syndrome. Clinically, it is associated with a pink gingiva with distinct stippling that covers nearly the entire tooth surface, frequently preventing their eruption. It is frequently reported during the transition from primary to permanent dentition, which left untreated may have a negative psychological impact at that age. The aim of this review is to provide a clinical insight, as well as a summary and discussion of the role of potential genes, chromosomal regions, and genetic variations in the pathogenesis of this rare disease. In addition, this paper describes a family with a non-syndromic form of hereditary gingival bromatosis exhibiting signicant clinical variability, ranging from severe generalized gingival overgrowth in a 19-year-old boy, to minimal manifestations in his maternal grandmother. The treatment modality used to treat this patient and measures taken to prevent the recurrence of this condition have also been discussed in detail.
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