Year-end Sale % OFF 
Abstract
Cyclic N‐sulfonyl ketimines constitute an accessible class of lead‐like heterocycles with a vast application in both synthetic organic and medicinal chemistry. In this context, we harness the capabilities of these heterocycles in four different isocyanide‐based multicomponent reactions. Our goal was to create libraries of compounds with functional groups and vectors that are compatible for structural elaboration and optimization of their physical properties. We synthesized 15 unprecedented compounds with high diversity and complexity, whereas we have obtained four single crystal structures of each scaffold, unraveling their geometrical features and potential employment in drug discovery.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
