Abstract

BackgroundBladder cancer (BC) treatment can have a detrimental effect on the sexual organs of patients and yet assessment of sexual health needs has been greatly overlooked for these patients compared to those who have undergone other cancer therapies.MethodsThis review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines in July 2019. Studies were identified by conducting searches for Medline (using the PubMed interface), the Cochrane Central Register of Controlled Trials (CENTRAL) and Ovid Gateway (Embase and Ovid) using a list of defined search terms.Results15 out of 37 studies included men only, 10 studies women only and 11 both sexes. Most participants were aged 50 to 65 years. Most studies (n = 34) focused on muscle invasive BC and only three on non-muscle invasive BC. Measurements of sexual dysfunction, including erection, ejaculation, firmness and desire, were the most commonly used measurements to report sexual health in men. In women, lubrification/dryness, desire, orgasm and dyspareunia were the most commonly reported. Twenty-one studies evaluated sexual dysfunction based on validated questionnaires, two with a non-validated questionnaire and through interviewing participants.ConclusionWhile recognition of the importance of the inclusion of psychometric measurements to assess sexual health is growing, there is a lack of consistent measures to assess sexual health in BC. With the focus on QoL arising in cancer survivorship, further studies are needed to develop, standardize and implement use of sexual health questionnaires with appropriate psychometrics and social measures to evaluate QoL in BC patients.Trial registration“PROSPERO does not currently accept registrations for scoping reviews, literature reviews or mapping reviews. PROSPERO is therefore unable to accept your application or provide a registration number. This decision should not stop you from submitting your project for publication to a journal.”

Highlights

  • Bladder cancer (BC) treatment can have a detrimental effect on the sexual organs of patients and yet assessment of sexual health needs has been greatly overlooked for these patients compared to those who have undergone other cancer therapies

  • With the focus on Health-related QoL (HRQoL) arising in cancer survivorship, it is needed to closely address and evaluate posttreatment sexual dysfunction and offer goal-directed treatment

  • The latter data was collected as sexual dysfunction may have an impact on HRQoL through effects on mental wellbeing (4)

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Summary

Introduction

Bladder cancer (BC) treatment can have a detrimental effect on the sexual organs of patients and yet assessment of sexual health needs has been greatly overlooked for these patients compared to those who have undergone other cancer therapies. It is well known that the diagnosis and treatment of cancer causes significant physical, psychological, and social effects that interfere with a person’s sexual health. It has been estimated that between 40 and 100% of cancer patients will experience a degree of sexual dysfunction [1]. The degree to which sexual dysfunction has been studied in different cancer types varies, with most studies performed in patients with prostate, breast or gynaecological cancers. The World Health Organization (WHO) defines sexual health as a state of physical, emotional, mental, and social wellbeing related to sexuality, and is not merely the absence of disease, dysfunction or infirmity [4]. Sexual health has to be evaluated holistically due to the complex interactions between biological, psychological, interpersonal and social/cultural factors [5], as all these factors may effect sexual function and wellbeing [6]

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