Abstract

The role of G-quadruplexes (GQP) in the life cycle of other viruses has led to the speculation that they may also have a function in the HIV genome. This paper aims to write-up on the potential of G-quadruplex as a potential anti-viral development. This paper narrates on (1) innovation of G-quadruplex detector, (2) location of G-quadruplex in HIV genome, (3) evidence and therapeutic approach using GQP as anti-HIV, and (4) contradiction on G-quadruplex utilization. The results of this investigation offer a quick insight on the use of G-quadruplex as a target and highlighting the potential of such intervention for antiviral treatments.

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