Abstract
On 12 September 2008, a tourist guide organising safari trips, residing in Lusaka, Zambia, was evacuated in a critical condition to Johannesburg, South Africa. She was admitted to a clinic where she died on 14 September about 10 days after the onset of symptoms. The symptoms included a prodromal phase with fever, myalgia, vomiting, diarrhoea, followed by rash, liver dysfunction and convulsions [1]. Cerebral oedema was detected on scan examination. No laboratory specimen was available for investigation.
Highlights
On 12 September 2008, a tourist guide organising safari trips, residing in Lusaka, Zambia, was evacuated in a critical condition to Johannesburg, South Africa
The paramedic who had cared for the index case during her evacuation to Johannesburg developed prodromal symptoms similar to the index case
An intensive care unit nurse who cared for the index case in Johannesburg developed similar flu-like symptoms and was hospitalised on 1 October
Summary
On 12 September 2008, a tourist guide organising safari trips, residing in Lusaka, Zambia, was evacuated in a critical condition to Johannesburg, South Africa. An intensive care unit nurse who cared for the index case in Johannesburg developed similar flu-like symptoms and was hospitalised on 1 October. Her condition deteriorated on 4 October and she died on 5 October of acute respiratory distress syndrome. Clinical symptoms of infection by arenaviruses in South America are similar to those described for Lassa fever in Africa. Reservoir of arenavirus and transmission Arenaviruses are associated with rodents, their natural hosts Some of these viruses can be transmitted to humans by contact with faeces, urine, blood or saliva of infected rodents or with dust containing infective particles. Since the 1970s special procedures for handling these viruses ( categorised as class 4 agents) have been put in place, including the building of dedicated biosafety laboratories (BSL-4), with containment equipment for all activities involving the virus, infectious or potentially infectious body fluids or tissues
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