Abstract

During the past decade, advances in device technology (eg, drug-eluting stents), development of safer anticoagulants (eg, bivalirudin), and refinement in procedural techniques have led to a dramatic improvement in the effectiveness and safety of percutaneous coronary intervention (PCI), despite increasing clinical and anatomic complexity of treated patients.1 As safety and effectiveness have been documented, the indications for PCI have expanded. In patients with ST-segment elevation myocardial infarction (STEMI), the superiority of primary PCI (when readily available) over thrombolytics is well established.2 More recently, PCI has also become a viable alternative to coronary artery bypass grafting in select patients with coronary artery disease.3 Article see p 14 As appreciation of the effectiveness of PCI has grown, there has been rapid diffusion of PCI capability into US hospitals. Dissemination of PCI has been further augmented by generous hospital and physician reimbursement, reductions in federal regulatory policies, and accumulating evidence that PCI can be performed safely at hospitals without on-site cardiac surgical backup.4,5 As a result, hospitals with PCI availability in the United States increased from 929 in 1993 to 1316 in 2004.6 Despite the growth in capacity, PCI is not available at all hospitals at all times. In fact, most patients with STEMI initially present to hospitals without PCI capability, where treatment options may include on-site thrombolytics or transfer to the nearest PCI-capable hospital for primary PCI. Based on demonstration of the superiority of primary PCI over thrombolytics,2 transfer to a PCI-capable hospital has been widely promoted as a treatment strategy for these patients.7 However, reperfusion in patients transferred for primary PCI is frequently delayed because <10% of these patients achieve the recommended door-to-balloon (D2B) time of <90 minutes.8 This is in sharp contrast to patients presenting directly to PCI-capable hospitals, where …

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.