United Kingdom OOKP outcomes

Abstract

AbstractThe osteo‐odonto‐keratoprosthesis (OOKP) is the only option for sight restoration in patients with end‐stage ocular surface blindness in eyes with severe dryness and eyelid anomalies or defective blink. OOKP is performed as a multistage procedure, which involves buccal mucosal grafting over the eye, OOKP device construction and its impanation into the eye in sequential steps. A retrospective study was conducted at Sussex eye hospital, Brighton, and the long‐term outcomes of the OOKP cases are presented here. In total 64 patients were included, and 74 laminae were implanted, which included 60 tooth autografts, 11 tooth allografts and 3 tibial grafts. Stevens‐Johnson syndrome was the most common indication accounting for 43% (n = 7) of the cases. Glaucoma was the most common complication noted in 86% (n = 57) of the cases. Laminar resorption was noted in 67% of the laminae. At 10 years of follow‐up, 59% of the eyes had a vision better than 6/12 and 82% had a vision better than 6/60. Autograft laminae showed a survival probability of 91% over 18 years. In summary, OOKP provides excellent visual recovery and longevity of the device over the long term; nevertheless, it requires close monitoring and timely interventions to treat any complications.