Abstract
Subependymomas are rare brain tumors derived from the ventricular system and are usually asymptomatic. The interest of this report is to demonstrate that subependymomas can very exceptionally present bilaterally and with hemorrhage. A 69-year-old woman presented with headache, ataxia, and focal neurologic deficits. Magnetic resonance imaging revealed a bilateral intra-axial lesion with unilateral hemorrhage. Patient underwent surgical resection of the tumor and the pathology was consistent with subependymoma. Postoperatively, patient recovered progressively with improvement of symptoms. This is the first case of a subependymoma that is both bilateral and hemorrhagic, two rare occurrences previously mutually exclusive in literature for this type of tumor. In the present case report we perform a review of the literature to analyze and compare retrospectively all other cases of hemorrhagic subependymomas.
Highlights
Subependymomas are rare benign neoplasms of the brain
Thirteen cases have been reported far [4]. This report presents this unique event of a bilateral supratentorial subependymoma with spontaneous hemorrhage
Their evolution is indolent and they don’t typically trigger symptoms or intracranial adverse events. These tumors are commonly smaller than 2 cm and greater sizes tend to produce symptoms associated with location [2] [4]. The exceptionality of this case lies in a symptomatic subependymoma presenting bilaterally with hemorrhagic transformation
Summary
Subependymomas are rare benign neoplasms of the brain They typically originate from the subependymal cell plate. (2015) Unique Occurrence of a Subependymoma Presenting Bilaterally with Hemorrhage: A Case Report. They typically arise in middle-aged and elderly men [2] [7]. 40% of quiescent subependymomas progress was slow growth and subsequently become symptomatic [1] If they become symptomatic, clinical presentation is usually triggered by cerebrospinal fluid obstruction or hydrocephalus (e.g., headache, nausea, vomiting, gait ataxia, vertigo and dizziness) or by compression of neural structures (e.g., focal neurologic deficits) [1] [4] [7]. Thirteen cases have been reported far [4] This report presents this unique event of a bilateral supratentorial subependymoma with spontaneous hemorrhage. We perform a review of the literature of hemorrhagic subependymomas
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