Abstract

Background: Hashimoto’s thyroiditis is an autoimmune disorder of thyroid gland. It is one of thecommon causes of hypothyroidism and is common in females. Generally, Hashimoto’s thyroiditisclinically presents as diffuse enlargement of the thyroid and nodular lesions are uncommon. But fewrecent studies from South India have shown that Hashimoto’s frequently presents as nodularenlargement of the thyroid. Such lesions can be easily confused with nodular goitre. Objectivesand Aim: Aim of the study is to study the clinicopathological features of Hashimoto’s thyroiditis andto estimate the frequency of nodular lesions in Hashimoto’s thyroiditis in a tertiary care healthcentre in coastal South India. Materials and Methods: The present study was done retrospectivelyon patients diagnosed as Hashimoto’s thyroiditis by fine-needle aspiration cytology during the periodJune 2017 to June 2020. Their clinical details, clinical examination findings including diffuse/nodularnature of the swelling, thyroid hormone status and ultrasound findings were studied. Results: In thepresent study, 102 cases of Hashimoto’s thyroiditis were included, which includes 91 females and 11males. Patients age ranged from 15 to 63 years with a peak in the fourth decade. Fifty-five cases(53.9%) were hypothyroid and 43 (42.2%) were euthyroid. Fifty cases (49%) presented as nodularlesion out of which 47 cases had multiple nodules. Conclusion: Nodular enlargement of the thyroidis a common finding in Hashimoto’s thyroiditis patients. Such cases should not be mistaken fornodular goitre as there is a risk of malignancy in Hashimoto’s thyroiditis.

Highlights

  • Hashimoto’s thyroiditis (HT) is one of the common causes of hypothyroidism, in the iodine sufficient areas [1,2]

  • Fine Needle Aspiration Cytology (FNAC) is a vital investigation which helps to confirm the diagnosis in suspected cases of HT [5,7]

  • Few recent studies from south India have shown that nodular enlargement of the thyroid gland is common in HT [8,9]

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Summary

Introduction

Hashimoto’s thyroiditis (HT) is one of the common causes of hypothyroidism, in the iodine sufficient areas [1,2]. Few recent studies from south India have shown that nodular enlargement of the thyroid gland is common in HT [8,9]. This assumes clinical significance because there is a risk for thyroid malignancy in patients with HT [2]. Materials and Methods: The present study was done retrospectively on patients diagnosed as Hashimoto’s thyroiditis by fine-needle aspiration cytology during the period June 2017 to June 2020 Their clinical details, clinical examination findings including diffuse/nodular nature of the swelling, thyroid hormone status and ultrasound findings were studied. Such cases should not be mistaken for nodular goitre as there is a risk of malignancy in Hashimoto’s thyroiditis

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Conclusion

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