Unilateral Urological Double Cancer after Kidney Transplantation

Abstract

In organ transplant patients, the high incidence of malignancy is well known. Here we experienced a simultaneous double cancer may occur after renal transplantation in the urinary tract. The patient was a 64-year-old woman. Diagnosis of renal failure undergoing Toxemia of pregnancy in 1971. Be introduced as end stage renal disease undergoing hemodialysis since 1978. Living donor kidney transplant performed in March 1980(The donor was her father). Renal transplantation immunosuppressive therapy was introduced azathioprine · methylprednisolone. Current maintenance immunosuppressive therapy is Mizoribine · methylprednisolone. Renal function after transplantation (2.3 to value 2.5 Serum creatinine) had remained in good condition. Admitted in January 2011, gross hematuria thereafter. No abnormal urine cytology tests, especially since no observation was also asymptomatic. Again showed gross hematuria in May 2011. Subject to the inspection report positive urine cytology again. Admitted to a space-occupying lesion in the left renal pelvis examination CT. Resection underwent left nephroureterectomy, July 29, 2011 left kidney tumor was diagnosed. Ureter were removed at the intersection of the left iliac artery. Pathological diagnosis of renal tissue excised Clear cell carcinoma, pT3a, G1> G2, Fuhrman grade 1, was INFa. Pathological diagnosis of the ipsilateral ureter was excised similarly invasive urothelial carcinoma of It ureter, G2, INFb, were pT1. Ureteral stump pathologic findings were observed in excised malignancy. Postoperative renal graft function is stable even without any particular change. We had have to be continued careful watching in our outpatient clinic. We report an example of urinary tract cancers occurring simultaneously in one side to the urinary tract 21 years after renal transplantation.