Abstract
Event related potentials were recorded from patients with unilateral temporal lobe lesions and healthy volunteers. Subjects were required to silently count on infrequent target tone interspersed among presentations of a non-target tone, with an interval between tones that was relatively long and variable (6-10s). Under these task conditions, the patients were found to have P300 amplitudes that were smaller on the lesioned side relative to the non-lesioned side. This finding is interpreted as evidence that temporal lobe lesions affect the configuration of intracranial sources generating the P300 component of event-related potentials.
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