Unilateral solitary erythema elevatum diutinum

Abstract

BackgroundErythema elevatum diutinum (EED) is a rare disease with unknown etiology, various presentations, broad spectrum of underlying conditions, and unified pathology. So, every case of it merits further investigation for better understanding of its causes and pathophysiology.Case presentationI report the case of a 32-year-old otherwise healthy man with an 8-year history of a refractory solitary lesion on his right hand and prompt response to dapsone 100 mg BID within 2 weeks without any recurrence after 2 years of follow-up.ConclusionThis case report aims to inform clinicians about EED in order to consider it in the differential diagnosis of any chronic refractory papule, nodule, or plaque on the relevant skin sites due to its protean manifestations, potential underlying diseases, and, finally, excellent response to dapsone.