Abstract
BackgroundTo report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure.Case presentationA 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis.ConclusionsThis is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported.
Highlights
Morning glory disc anomaly (MGDA) is a rare congenital anomaly of the optic disc and peripapillary retina [1, 2]
This is the first report to suggest an association between prenatal Zika virus (ZIKV) exposure and morning glory disc anomaly (MGDA)
Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported
Summary
This is the first report to suggest an association between prenatal ZIKV exposure and MGDA.
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