Unilateral Inflammatory Linear Verrucous Epidermal Naevus of the Face and the Oral Mucosa. A Rare Case

Abstract

Epidermal nevi are a group of hamartomatous lesions of the skin consisting of an overgrowth of the normal components of the epidermis and adnexal structures. The clinical manifestations include yellowish-brown, granular or papillomatuous plaques typically arranged in a linear or whorled configuration following Blaschko's lines. These lesions are usually observed at birth and they enlarge slowly during childhood. Then, they tend to stabilize by adolescence [1]. Epidermal nevus syndrome (ENS) is a condition where the epidermal nevi are associated with the involvement of other organ systems notably neurological, ocular, cardiovascular and urological developmental abnormalities. It has been reported that 30% of individuals with epidermal nevi have additional syndrome symptoms [2,1]. Oral involvement is extremely rare [3]. and only few cases have been reported in the literature. The aim of this paper was to report the case of a 9-year-old patient with inflammatory linear verrucous epidermal nevus of his right cheek with an intra-oral involvement of his buccal mucosa. To discuss different treatment modalities and possible outcomes.