Unilateral Herpetik Keratitli Hastalarda Kuru Göz Parametrelerinin Değerlendirilmesi

Abstract

Objective: Our aim in this study was to examine the tear parameters between affected and unaffected eyes of unilateral herpes simplex virus (HSV) keratitis patients, especially the meibomian glands status. Methods: The examinations and tear parameters including; tear film meniscus height (TMH) and area (TMA), non-invazive break up time (NIBUT), schirmer test, meibomian gland’s ekspressibility grade, drop out grade and microstructure of patients who were treated in our clinic with the diagnosis of unilateral herpetic endothelitis or herpetic stromal keratitis, and who had a quiescent period of about 3 months, were evaluated retrospectively. Results: The median age of our patients was 58.0 (55.25-72.25) years. The median NIBUT was 6.85 (4.62-17.0) sec. in affected eye and 15.85 (10.47-17.15) sec. in unaffected eye. NIBUT values were observed to be remarkable lower in the affected eye, although the change between groups was not statistically significant. Schirmer test values, TMH and TMA were similar between affected and unaffected eyes. Meibomian gland evaluations of affected and unaffected eyes were shown similar distribution across meibomian expressibility and drop out grades. Conclusion: We observed similar effects in both morphological and microstructural features of meibomian glands in both eyes. This condition makes us think that the developing dry eye disease in both eyes may be caused not only by neurosensorial anomalies but also by changes in the meibomian glands.