Abstract

We report two cases of unilateral gustatory flushing presenting in infancy. This is considered to be a variant of Frey’s syndrome, whereby in children, aberrant sweating is often absent. It occurs as a result of damage, either following perinatal birth trauma or infection. Misdirected regeneration of the parasympathetic fibres of the auriculotemporal nerve results in localised erythema occurring in a fixed distribution. In children, this condition is harmless, spontaneous resolution has been reported and no treatment is required. However, more recently botulinum toxin injections have been proposed for adolescents in whom this may be socially distressing.

Highlights

  • We report two cases of unilateral gustatory flushing presenting in infancy

  • We report two cases of unilateral facial flushing of different aetiology, highlighting the spectrum of disease and reviewing the need to consider Frey’s syndrome as the cause for this presenting complaint

  • Unilateral gustatory flushing of unknown aetiology is rare, with around 70 cases reported in the literature, to date

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Summary

Introduction

We report two cases of unilateral gustatory flushing presenting in infancy. This is considered to be a variant of Frey’s syndrome, whereby in children, aberrant sweating is often absent. It comprises recurrent episodes of gustatory flushing and/or sweating occurring in the distribution of the auriculotemporal nerve, which arises from the mandibular division of the trigeminal nerve [2]. We report two cases of unilateral facial flushing of different aetiology, highlighting the spectrum of disease and reviewing the need to consider Frey’s syndrome as the cause for this presenting complaint.

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