Abstract
An 83-year-old woman presented with accumulations of pigment in the anterior chamber of her right (Fig A) but not left eye (Fig B). Fundus examinations, gonioscopy, B-scan ultrasonography (Fig C), and ultrasound biomicroscopy failed to identify an intraocular tumor. An iris biopsy revealed a proliferation of melanocytes without atypia (Fig D), which were intensively immunoreactive for Melan A (Fig E). A diagnosis of unilateral diffuse uveal melanocytic proliferation was established. Later, the patient revealed she had a small cutaneous melanoma removed from her back 50 years prior.
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