Unilateral Blepharoconjunctivitis due to Monkeypox Virus Infection

Abstract

A 35-year-old Italian man presented with unilateral ocular pain and photophobia that started 7 days before presentation. Anterior segment examination (aided by asking the patient to pull down his lower eyelid; Fig A-B) revealed multiple (> 10) umbilicated papules on the tarsal and bulbar conjunctiva, the fornix, and at the temporal limbus; the fellow eye was uninvolved. He had multiple cutaneous, genital, oropharyngeal and anal vesicular-pustular lesions, generalized lymphadenopathy, and fever (Fig C-D).