Unifying criteria for dissolution kinetics of various hydroxyapatite preparations

Abstract

A powder suspension method has been used to study the dissolution rate behavior of various hydroxyapatite (HAP) preparations in acidic media containing different levels of calcium and phosphate. Despite the reported variabilities in the properties among differently prepared samples, the present study indicates that, with regard to the dissolution rate behavior, there is an important common characteristic dissolution rate component. There appears to be a dissolution site common to most HAP preparations that may be associated with the predominant surface of the HAP crystal. Also, an attempt is made to correlate the dissolution rate data with the study of Young and Holcomb on the properties of different HAP preparations.