Abstract

Air pollution exposure is associated with adverse reproductive outcomes, however, the impact of an acute episode of unhealthy air quality on in vitro fertilization (IVF) outcomes has not been studied. The historic September 2020 Oregon wildfires caused an unprecedented air quality crisis with an increase in average air quality index from 26 (Good) in the preceding 2 months to 336 (Hazardous) over a 10-day period. To evaluate the relationship between unhealthy air quality and IVF outcomes, we compared IVF cycle outcomes during a 10-day period of unhealthy air quality to IVF cycles from 2 months prior.

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