Abstract
As one of the leading causes of hypercalcemia, malignancy is an essential consideration when patients present with such symptomology. While certain tumors are more known to cause hypercalcemia, it can occur with almost any type of cancer. Hodgkin lymphoma is an infrequent cause of hypercalcemia. Only a few case reports have been published in the literature to date. We report an unusual case of a 61-year-old female who presented with altered mental status, nausea, vomiting, and dizziness and was found to have multiple enlarged lymph nodes, and blood work showed hypercalcemia. Biopsy of the cervical lymph node showed Hodgkin lymphoma of the nodular sclerosis subtype. Our case aims to raise awareness of this rare but significant presentation of hypercalcemia and how timely treatment of calcium levels can facilitate the employment of available chemotherapeutic options.
Highlights
Hypercalcemia is a common paraneoplastic syndrome encountered in oncology practice, constituting up to 30% of patients with cancers [1]
While hypercalcemia is more frequent with certain tumors than others, it could be encountered in various types of malignancies
While it is not uncommon to observe hypercalcemia with non-Hodgkin lymphoma, it is scarcely found with Hodgkin lymphoma
Summary
Hypercalcemia is a common paraneoplastic syndrome encountered in oncology practice, constituting up to 30% of patients with cancers [1]. Elevated calcium and resultant symptomology are often the initial triggers for investigation. Hypercalcemia is an adverse prognostic factor in malignancy. While hypercalcemia is more frequent with certain tumors than others, it could be encountered in various types of malignancies. We are reporting a unique case of hypercalcemia associated with Hodgkin lymphoma
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