Abstract
PurposeTo report the incidence and clinical features of patients that experienced un-explained visual loss following silicone oil (SO) removal.MethodsMulticenter retrospective study of patients that underwent SO removal during 2000–2012. Visual loss of ≥2 lines was considered significant.ResultsA total of 324 eyes of 324 patients underwent SO removal during the study period. Forty two (13%) eyes suffered a significant visual loss following SO removal. Twenty three (7.1%) of these eyes lost vision secondary to known causes. In the remaining 19 (5.9%) eyes, the loss of vision was not explained by any other pathology. Eleven of these 19 patients (57.9%) were male. The mean age of this group was 49.2 ± 16.4 years. Eyes that had an un-explained visual loss had a mean IOP while the eye was filled with SO of 19.6 ± 6.9 mm Hg. The length of time that the eye was filled with SO was 14.8 ± 4.4 months. In comparison, eyes that did not experience visual loss had a mean IOP of 14 ± 7.3 mm Hg (p < 0.0002) and a mean tamponade duration of 9.3 ± 10.9 months (p < 0.0001).ConclusionsAn un-explained visual loss after SO removal was observed in 5.9% of eyes. Factors associated with this phenomenon included a higher IOP and longer SO tamponade duration.
Highlights
Silicone oil (SO) has long been used as a long term intraocular tamponading agent for complex retinal detachments associated with severe proliferative vitreoretinopathy (PVR) [1], giant retinal tears (GRT) [2], tractional retinal detachment in proliferative diabetic retinopathy [3, 4], viral retinitis [5, 6], and trauma with PVR [7, 8]
In 11 patients 5000 cs SO was used and in 8 eyes 1000 cs SO was used. In all of these cases the retina remained attached during the silicone oil fill and following its removal
SD-OCT and FA were performed in all these cases and did not reveal any causes of acute visual loss such as cystoid macular edema, epiretinal membrane or macular ischemia
Summary
Silicone oil (SO) has long been used as a long term intraocular tamponading agent for complex retinal detachments associated with severe proliferative vitreoretinopathy (PVR) [1], giant retinal tears (GRT) [2], tractional retinal detachment in proliferative diabetic retinopathy [3, 4], viral retinitis [5, 6], and trauma with PVR [7, 8]. Our purpose is to report the incidence and clinical features of patients that experienced un-explained visual loss following SO removal
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