Unexpected Uptake by the Gallbladder in Post-Ablative I-131 Scan.

Kemal Ünal,Özgür Ümit Akdemir

doi:10.4274/mirt.57441

Kemal Ünal, Özgür Ümit Akdemir

Open Access

https://doi.org/10.4274/mirt.57441

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Abstract

A 47-year-old woman was diagnosed as papillary thyroid carcinoma. I-131 ablation therapy was applied following total thyroidectomy, and the whole-body scan revealed a focus of increased uptake in the right upper quadrant. Lateral view images of the uptake site showed that the focus was located near the right liver lobe. The patient was referred to radiology department for correlative abdominal Computed Tomography (CT) and Ultrasonography (US) to rule out a possible liver metastasis. CT images detected a gallstone in the corresponding area, which was verified by US. These methods did not reveal any metastatic disease in the liver or in other abdominal organs. This is the first published case report documents a rare false-positive finding of I-131 scan that was associated with an asymptomatic gallstone, and emphasizes the importance of correlative imaging in gallbladder related I-131 uptake.

Highlights

I-131 ablation therapy is widely used for the treatment of well-differentiated thyroid cancer
No funds were received from any organizations: National Institutes of Health (NIH); Wellcome Trust; Howard Hughes Medical Institute (HHMI); and other(s)
The patient was referred to radiology department for correlative abdominal Computed Tomography (CT) and US, to rule out a possible liver metastasis

Summary

Introduction

I-131 ablation therapy is widely used for the treatment of well-differentiated thyroid cancer. Uzak metastatik bir odak hastanın prognozunu değiştireceğinden, beklenmedik bir karaciğer metastazını ekarte etmek ve anatomik korelasyon sağlamak amacıyla hastaya yapılan abdominal Bilgisayarlı Tomografi (BT) ve ultrasonografi tetkiklerinde safra taşı rapor edildi. Anahtar Kelimeler: İyot-131, tiroid kanseri, safra taşı Post-ablative scan is a sensitive method for diagnosis of metastatic or residual disease.

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