Abstract

F-18 FDG PET-CT scanning plays an important role in the management of fever of unknown origin (FUO). Some elderly patients with FUO can be in their terminal stage of life. An elderly woman was referred for a PET-CT scan to find the etiology of FUO. The scan was inconclusive but showed significantly reduced FDG uptake in the brain and heart, despite normal physiological uptake in the liver and bowel. The patient deceased within the hour post scan. Contrary to common belief, we have shown that cerebral glucose metabolism via cerebral perfusion may be compromised before hepatic and bowel perfusion in a dying patient. Conflict of interest:None declared.

Highlights

  • Case ReportMolecular Imaging and Radionuclide Therapy 2012;21(2): 88-90 DOI:10.4274/Mirt.136

  • F-18 FDG PET-CT scanning has become widely available as a new radiological and nuclear medicine investigation, it is by large considered as a tool of non-acute clinical management such as oncology staging [1], monitoring response to therapies [2], detection of disease recurrence [3] and detection of unknown primary malignancies [4] or infection/inflammation [5]

  • It is widely believed cerebral perfusion and glucose metabolism may be sustained until all peripheral perfusion is compromised in a dying patient

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Summary

Case Report

Molecular Imaging and Radionuclide Therapy 2012;21(2): 88-90 DOI:10.4274/Mirt.136. Ölmekte Bir Hastada Normal Karaciğer Uptake’ine Karşın Serebrumda Beklenmeyen Belirgin Düşük FDG Tutulumu.

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