Abstract

Department of Chemistry Education, Sunchon National University, Sunchon 540-742, Korea Received May 22, 2014, Accepted July 15, 2014Key Words : Macrocycle, Intramolecular cyclization, Hydroamination, Alkyne, Topologically constrainedmacrocycleThe reaction of amines with alkynes, which is commonlyknown as hydroamination, has attracted considerable atten-tion because it can be a useful organic transformation toform biologically important unsaturated heterocycles.

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