Unexpected Finding of an Inverted Appendix on Screening Colonoscopy

Abstract

Question: A healthy 66-year-old woman underwent screening colonoscopy for positive fecal immunochemical test. She reported intermittent per rectal bleeding for a few years without anemia and had never had a colonoscopy or appendicectomy. She took thyroxine for hypothyroidism and there was no family history of gastrointestinal malignancy. Colonoscopy showed a 2-cm tubular lesion with normal overlying mucosa, arising at the expected appendiceal orifice location (Figure A and B), which was not biopsied due to clinical suspicion of an inverted appendix.