Abstract

Objectives To assess whether different genomic cell-free DNAs are equally abundant in the plasma of individual donors, and any relationship between DNA methylation and representation in plasma. Design and methods The concentrations of DNA in plasma were determined by real-time PCR. Results Different DNA sequences were not equally represented. The relative abundances were similar in different donors. Conclusions Different DNA sequences are not equally abundant in plasma, with no relationship between DNA methylation and abundance.

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