Abstract

AbstractAbout a case of pulmonary granulomatosis disease first diagnosed as a tuberculosis from thoracic X ray examination; anamnesis, thoracic scanner and biological analyses established diagnosis of sarcoidosis which could be confirmed by pathological analysis of cutaneous lesions found after deep physical examination. Biological analyses showed that intern organs were also injured; corticoid therapy easily cured the disease with normalized biological values. The increase in serum angiotensin converting enzyme activity (ACE) is not specific for sarcoidosis but guides the physician toward diagnosis in this case and can follow efficacy of the therapy. Serum ACE activity is determined by spectrophotometric methods developed on biochemistry automates.

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