Abstract
Osteosarcoma (OS) is the most common primary malignant tumor of bone. However, osteosarcoma located in the jaw (JOS) is rare, aggressive and malignant, constituting 5% to 13% of all cases of skeletal OS. JOS has a male predilection with 34 to 36 years old. Prognostic is associated with several variables, such as tumor location, initial size, existence or absence of metastasis, gender, age, cytogenetic chances and respond to chemotherapy. We report the unusual case of osteosarcoma in the mandible on retromolar area arising from primitive bone forming mesenchyme; most often arises in the metaphysis of long bones of the extremities.
Highlights
According to World Health Organization (WHO), osteosarcoma (OS) is the most common primary malignant tumor of bone, accounting for approximately 35 percent of cases, followed by chondrosarcoma (25%), and Ewing sarcoma (16%), and occurs predominantly in patients younger than age of twenty, and in this group 80% occur in long bones of the extremities [1]
Prognostic is associated with several variables, such as tumor location, initial size, existence or absence of metastasis, gender, age, cytogenetic chances and response to chemotherapy pre surgery [7]
The patient was referred to head and neck surgery service where it was held M-section of the mandible (Figure 5 and Figure 6), 10 sessions of chemotherapy and 20 sessions radiotherapy
Summary
According to World Health Organization (WHO), osteosarcoma (OS) is the most common primary malignant tumor of bone, accounting for approximately 35 percent of cases, followed by chondrosarcoma (25%), and Ewing sarcoma (16%), and occurs predominantly in patients younger than age of twenty, and in this group 80% occur in long bones of the extremities [1]. Panoramic radiography remains the primary means of diagnosis, where the image the “sun ray” shows pathognomonic signal, CT images provide high quality and excellent anatomic resolution, providing visualization of tumor calcification and cortical bone involvement, being of great importance in the diagnostic and treatment planning. The emergence of this disease at the trigonoretromolar region (oblique line) is the novelty of this clinical case. The patient was referred to head and neck surgery service where it was held M-section of the mandible (Figure 5 and Figure 6), 10 sessions of chemotherapy and 20 sessions radiotherapy
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