Abstract
Myocardial infarctions (MI) are relatively common in people with deep vein thrombosis (DVT). In fact, the rate of myocardial infarction has been reported to be greater in adults with DVT as compared to those without DVT and recent studies have shown interest in quantifying the relationship with MI and DVT. However, cryptogenic nature of MI in these individuals is underestimated. Approximately one-fourth of the US populations are estimated to have a patent foramen ovale (PFO). Of note, since MI being the single largest cause of mortality, a large number of these patients have a PFO. The high percentage of myocardial infarction in patients with a PFO has not been addressed in the literature appropriately before and might have been overlooked because most of the patients with infarctions had an uncomplicated course and only moderate enzyme elevation.
Highlights
Patent foramen ovale (PFO) is a condition where an openingThrombosis: Short Review
Risk factors there are transient episodes of right-to-left intracardiac shunting for paradoxical coronary embolism (PCE) with PFO include previous or current pulmonary emboli, associated with increased right atrial pressures that occur with pregnancy, factor Leiden deficiency, ischemic stroke and various
Deep vein thrombosis (DVT) is associated with pathologic changes and physiologic adaptations that can lead to cryptogenic myocardial infarction in the setting of a PFO
Summary
Patent foramen ovale (PFO) is a condition where an openingThrombosis: Short Review. J Clin Nutr Diet. 2016, 2:3.that exists between the left and right atria of the heart. PFO with intracardiac without overt cardiac symptoms, presumably related to patent shunting is associated with cryptogenic myocardial infarction foramen ovale have been described [7]. Risk factors there are transient episodes of right-to-left intracardiac shunting for PCE with PFO include previous or current pulmonary emboli, associated with increased right atrial pressures that occur with pregnancy, factor Leiden deficiency, ischemic stroke and various
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