Abstract
Despite the recent development of effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), non-pharmaceutical interventions will remain the cornerstone in the battle against COVID-19 for some time. Such interventions are effective but have major societal and economic impacts and should therefore be used as selectively as possible. Quarantine after exposure to a patient with COVID-19 is such a measure. Reported secondary-attack rates among so-called high-risk contacts have varied widely from lower than 1% to 54·9%.
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