Abstract
Glycated Human Serum Albumin (GHSA) (glucose-bound albumin) is found to act as a diabetes biomarker. Many attempts have been made to quantify GHSA level. Fluorescent aptasensor is one of potential techniques for detect GHSA. To detect GHSA, GHSA-selective aptamer is quenched by graphene surface. A presence of GHSA in a sample causes the desorption of aptamer to form the aptamer-GHSA complex in solution. The mechanism of GHSA-aptamer-GRA complex is important for aptasensor efficiency. This step is a key for aptasensor function.
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